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Bipolar Disorder: What do Genes Have to do with it?

Dr. Jordan Smoller

Dr. Jordan Smoller is Associate Vice Chair of the MGH Department of Psychiatry and Director of Psychiatric Genetics. He is Professor of Psychiatry at Harvard Medical School and Associate Professor in the Department of Epidemiology at the Harvard School of Public Health in Boston.  He is Director of the Psychiatric and Neurodevelopmental Genetics Unit in the MGH Center for Human Genetics Research. Dr. Smoller also serves as co-director of the Genetics and Genomics Unit of the MGH Clinical Research Program. At Harvard Medical School, he has served as Director of the Translational Genetics and Bioinformatics Program of the Harvard Catalyst. He is also Science Director of the Science of Health and Development Initiative at the Center on the Developing Child at Harvard University. Dr. Smoller is an Associate Member of the Broad Institute and a Senior Scientist at the Broad's Stanley Center for Psychiatric Research.

Dr. Smoller earned his undergraduate degree at Harvard University and his medical degree at Harvard Medical School.  After completing residency training in psychiatry at McLean Hospital, Dr. Smoller received masters and doctoral degrees in epidemiology at the Harvard School of Public Health. He also completed a postdoctoral fellowship in the NIMH Training Program in Psychiatric Genetics.

The focus of Dr. Smoller's research interests has been the identification of genetic determinants of childhood and adult psychiatric disorders.  Dr. Smoller and colleagues have also been studying pharmacogenetic predictors of treatment response and the ways in which advances in genetics may impact clinical practice in psychiatry. He is an author of more than 200 scientific articles, book chapters and reviews; the recipient of numerous research awards; and a principal investigator on NIH-funded studies of the genetics of anxiety and the genetics of bipolar disorder, major depression and schizophrenia as well as brain imaging phenotypes. He is also the author of The Other Side of Normal (HarperCollins/William Morrow, 2012).